Development of artesunate intelligent prodrug liposomes based on mitochondrial targeting strategy

Development of artesunate intelligent prodrug liposomes based on mitochondrial targeting strategy

Abstract Breast cancer is the leading cause of cancer-related deaths in women and remains a formidable therapeutic challenge. Mitochondria participate in a myriad of essential cellular processes, such as metabolism, and are becoming an ideal target for cancer therapy. Artemisinin and its derivatives...

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Bibliographic Details
Main Authors: Liwei Gu, Jiaxing Zhang, Dandan Liu, Jiayun Chen, Shuzhi Liu, Qing Peng, Ya Tian, Maobo Du, Junzhe Zhang, Wei Xiao, Shuo Shen, Jigang Wang
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Journal of Nanobiotechnology
Subjects:
Artesunate smart conjugate
Mitochondrial targeting
Liposomes
Anti-tumor
Mitophagy
Online Access:https://doi.org/10.1186/s12951-022-01569-5

Internet

https://doi.org/10.1186/s12951-022-01569-5

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