Previous cardiovascular injury is a prerequisite for immune checkpoint inhibitor‐associated lethal myocarditis in mice

Previous cardiovascular injury is a prerequisite for immune checkpoint inhibitor‐associated lethal myocarditis in mice

Abstract Aims Immune checkpoint inhibitors (ICIs) are antineoplastic drugs designed to activate the immune system's response against cancer cells. Evidence suggests that they may lead to immune‐related adverse events, particularly when combined (e.g., anti‐CTLA‐4 plus anti‐PD‐1), sometimes resu...

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Bibliographic Details
Main Authors: Nestor Rubio‐Infante, Elena Cristina Castillo, Hugo Alves‐Figueiredo, Martin Ramos‐González, Felipe Salazar‐Ramírez, Daniel Salas‐Treviño, Adolfo Soto‐Domínguez, Omar Lozano, Gerardo García‐Rivas, Guillermo Torre‐Amione
Format: Article
Language:English
Published: Wiley 2024-04-01
Series:ESC Heart Failure
Subjects:
Heart damage
Heart failure
Immune checkpoint inhibitors
Inflammation
Myocarditis
Online Access:https://doi.org/10.1002/ehf2.14614

Internet

https://doi.org/10.1002/ehf2.14614

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