Overexpression of ERG and Wild-Type PTEN Are Associated with Favorable Clinical Prognosis and Low Biochemical Recurrence in Prostate Cancer.

The aim of this study was to investigate the expression of two commonly altered genes ERG and PTEN in prostate cancer (PC) and evaluate their prognostic significance. Despite conflicting published results, TMPRSS2-ERG gene fusion and PTEN loss are generally considered unfavorable markers for PC prog...

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Main Authors: Sung Han Kim, Soo Hee Kim, Jae Young Joung, Geon Kook Lee, Eun Kyung Hong, Kyung Min Kang, Ami Yu, Byung Ho Nam, Jinsoo Chung, Ho Kyung Seo, Weon Seo Park, Kang Hyun Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4405492?pdf=render