Secreted Soluble Factors from Tumor-Activated Mesenchymal Stromal Cells Confer Platinum Chemoresistance to Ovarian Cancer Cells

Secreted Soluble Factors from Tumor-Activated Mesenchymal Stromal Cells Confer Platinum Chemoresistance to Ovarian Cancer Cells

Ovarian cancer (OC) ranks as the second most common type of gynecological malignancy, has poor survival rates, and is frequently diagnosed at an advanced stage. Platinum-based chemotherapy, such as carboplatin, represents the standard-of-care for OC. However, toxicity and acquired resistance to ther...

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Bibliographic Details
Main Authors: Yifat Koren Carmi, Hazem Khamaisi, Rina Adawi, Eden Noyman, Jacob Gopas, Jamal Mahajna
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:International Journal of Molecular Sciences
Subjects:
chemoresistance
HGF
IL-6
kinase inhibitors
ovarian cancer
tumor microenvironment
Online Access:https://www.mdpi.com/1422-0067/24/9/7730

Internet

https://www.mdpi.com/1422-0067/24/9/7730

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