ATAD2 promotes glycolysis and tumor progression in clear cell renal cell carcinoma by regulating the transcriptional activity of c-Myc

Abstract Clear cell renal cell carcinoma (ccRCC) is a common malignant tumor of the urogenital tract. Given that ccRCC is often resistant to radiotherapy and traditional chemotherapy, the clinical treatment of patients with ccRCC remains a challenge. The present study found that ATAD2 was significan...

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Bibliographic Details
Main Authors: Zonglong Wu, Liyuan Ge, Yimeng Song, Shaohui Deng, Peichen Duan, Tan Du, Yaqian Wu, Zhanyi Zhang, Xiaofei Hou, Lulin Ma, Shudong Zhang
Format: Article
Language:English
Published: Springer 2023-05-01
Series:Discover Oncology
Subjects:
Online Access:https://doi.org/10.1007/s12672-023-00696-1