Conjugates of Iron-Transporting <i>N</i>-Hydroxylactams with Ciprofloxacin

Conjugates of Iron-Transporting <i>N</i>-Hydroxylactams with Ciprofloxacin

Screening of a library of novel <i>N</i>-hydroxylactams amenable by the Castagnoli-Cushman reaction identified four lead compounds that facilitated <sup>55</sup>Fe transport into <i>P. aeruginosa</i> cells (one of these synthetic siderophores was found to be as ef...

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Bibliographic Details
Main Authors: Olga Bakulina, Anton Bannykh, Ekaterina Levashova, Mikhail Krasavin
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Molecules
Subjects:
Castagnoli-Cushman reaction
cyclic hydroxamic acids
siderophores
bacterial iron transport
Trojan horse antibiotics
Online Access:https://www.mdpi.com/1420-3049/27/12/3910

Internet

https://www.mdpi.com/1420-3049/27/12/3910

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