Apigenin alleviates diabetic endothelial dysfunction through activating AMPK/PI3K/Akt/eNOS and Nrf2/HO‐1 signaling pathways

Abstract Apigenin (4′,5,7‐trihydroxyflavone) is a natural flavone reported to present anti‐diabetic and anti‐oxidative bioactivities. The effect of apigenin to mitigate endothelial dysfunction in diabetes remains to be investigated. In the present study, the vaso‐protective effect of apigenin as wel...

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Bibliographic Details
Main Authors: Lingchao Miao, Meng Sam Cheong, Chunxiu Zhou, Mohamed Farag, Wai San Cheang, Jianbo Xiao
Format: Article
Language:English
Published: Wiley 2023-03-01
Series:Food Frontiers
Subjects:
Online Access:https://doi.org/10.1002/fft2.192