Reduction in Lens Epithelial Cell Senescence Burden through Dasatinib Plus Quercetin or Rapamycin Alleviates D-Galactose-Induced Cataract Progression

Reduction in Lens Epithelial Cell Senescence Burden through Dasatinib Plus Quercetin or Rapamycin Alleviates D-Galactose-Induced Cataract Progression

Senescent cells accumulate in aged organisms and promote the progression of age-related diseases including cataracts. Therefore, we aimed to study the therapeutic effects of senescence-targeting drugs on cataracts. In this study, a 28-day D-galactose-induced cataract rat model was used. The opacity...

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Bibliographic Details
Main Authors: Yinhao Wang, Yulin Tseng, Keyu Chen, Xinglin Wang, Zebin Mao, Xuemin Li
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Journal of Functional Biomaterials
Subjects:
cataract
senescence
senolytic
senescence-associated secretory phenotype
Online Access:https://www.mdpi.com/2079-4983/14/1/6

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https://www.mdpi.com/2079-4983/14/1/6

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