RIPK1 or RIPK3 deletion prevents progressive neuronal cell death and improves memory function after traumatic brain injury

RIPK1 or RIPK3 deletion prevents progressive neuronal cell death and improves memory function after traumatic brain injury

Abstract Traumatic brain injury (TBI) causes acute and subacute tissue damage, but is also associated with chronic inflammation and progressive loss of brain tissue months and years after the initial event. The trigger and the subsequent molecular mechanisms causing chronic brain injury after TBI ar...

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Bibliographic Details
Main Authors: Antonia Clarissa Wehn, Igor Khalin, Marco Duering, Farida Hellal, Carsten Culmsee, Peter Vandenabeele, Nikolaus Plesnila, Nicole Angela Terpolilli
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Acta Neuropathologica Communications
Subjects:
Traumatic brain injury
Chronic posttraumatic brain damage
Magnetic resonance imaging
Necroptosis
Ferroptosis
Neuroprotection
Online Access:https://doi.org/10.1186/s40478-021-01236-0

Internet

https://doi.org/10.1186/s40478-021-01236-0

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