The NRF2, Thioredoxin, and Glutathione System in Tumorigenesis and Anticancer Therapies

Cancer remains an elusive, highly complex disease and a global burden. Constant change by acquired mutations and metabolic reprogramming contribute to the high inter- and intratumor heterogeneity of malignant cells, their selective growth advantage, and their resistance to anticancer therapies. In t...

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Bibliographic Details
Main Authors: Morana Jaganjac, Lidija Milkovic, Suzana Borovic Sunjic, Neven Zarkovic
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Antioxidants
Subjects:
Online Access:https://www.mdpi.com/2076-3921/9/11/1151