A Novel Network Science and Similarity-Searching-Based Approach for Discovering Potential Tumor-Homing Peptides from Antimicrobials

A Novel Network Science and Similarity-Searching-Based Approach for Discovering Potential Tumor-Homing Peptides from Antimicrobials

Peptide-based drugs are promising anticancer candidates due to their biocompatibility and low toxicity. In particular, tumor-homing peptides (THPs) have the ability to bind specifically to cancer cell receptors and tumor vasculature. Despite their potential to develop antitumor drugs, there are few...

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Bibliographic Details
Main Authors: Maylin Romero, Yovani Marrero-Ponce, Hortensia Rodríguez, Guillermin Agüero-Chapin, Agostinho Antunes, Longendri Aguilera-Mendoza, Felix Martinez-Rios
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Antibiotics
Subjects:
cancer
tumor-homing peptide
in silico drug discovery
complex network
chemical space network
centrality measure
Online Access:https://www.mdpi.com/2079-6382/11/3/401

Internet

https://www.mdpi.com/2079-6382/11/3/401

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