Mining and visualizing high-order directional drug interaction effects using the FAERS database

Mining and visualizing high-order directional drug interaction effects using the FAERS database

Abstract Background Adverse drug events (ADEs) often occur as a result of drug-drug interactions (DDIs). The use of data mining for detecting effects of drug combinations on ADE has attracted growing attention and interest, however, most studies focused on analyzing pairwise DDIs. Recent efforts hav...

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Bibliographic Details
Main Authors: Xiaohui Yao, Tiffany Tsang, Qing Sun, Sara Quinney, Pengyue Zhang, Xia Ning, Lang Li, Li Shen
Format: Article
Language:English
Published: BMC 2020-03-01
Series:BMC Medical Informatics and Decision Making
Subjects:
High-order drug interaction
Directional effect
FAERS
Apriori
Sunburst
Online Access:http://link.springer.com/article/10.1186/s12911-020-1053-z

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http://link.springer.com/article/10.1186/s12911-020-1053-z

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