Acetylcholinesterase inhibition and antimicrobial activity of hydroxyl amides synthesized from natural products derivatives

Acetylcholinesterase inhibition and antimicrobial activity of hydroxyl amides synthesized from natural products derivatives

ABSTRACT Thirteen natural products derivatives of hydroxyl amide class, three described for the first time, were synthesized by reaction of three indole acids and 3,4,5-trimethoxybenzoic acid with six different amino alcohols in the presence of triphenylphosphine and N-bromosuccinimide. The derivati...

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Bibliographic Details
Main Authors: MARIA AMÉLIA D. BOAVENTURA, LAURA F.W. XAVIER, HENRIETE S. VIEIRA, JACQUELINE A. TAKAHASHI, WILTON J.D. NASCIMENTO JUNIOR, TAMIRES P. ARAUJO, AMANDA C.S. COELHO
Format: Article
Language:English
Published: Academia Brasileira de Ciências 2018-06-01
Series:Anais da Academia Brasileira de Ciências
Subjects:
acetylcholinesterase inhibition
antimicrobial activity
indole acid derivatives
3,4,5-trimethoxybenzoic acid derivatives
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652018000501945&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652018000501945&lng=en&tlng=en

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