Iron overload and chelation modulates bisretinoid levels in the retina
AimIron dysregulation in conjunction with other disease processes may exacerbate retinal degeneration. We employed models of iron overload and iron chelation to explore the interactions between iron-catalyzed oxidation and photoreactive bisretinoid lipofuscin.MethodsThe mice were injected intravitre...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2023-12-01
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Series: | Frontiers in Ophthalmology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fopht.2023.1305864/full |