Paeonol enhances macrophage phagocytic function by modulating lipid metabolism through the P53-TREM2 axis

Paeonol enhances macrophage phagocytic function by modulating lipid metabolism through the P53-TREM2 axis

Introduction: The emerging concept of immunometabolism highlights the interplay between lipid metabolism and phagocytosis in macrophages. Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) has been identified as an essential modulator of both lipid metabolism and phagocytic function in macroph...

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Bibliographic Details
Main Authors: Jifei Miao, Xiaoming Liu, Yuanpin Liao, Yiwen Li, Yingyan Kuang, Juanxia Zheng, Zigang Li, Jiao Lan
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Pharmacology
Subjects:
phagocytosis
lipid metabolism
TREM2
p53
macrophage
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1214756/full

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https://www.frontiersin.org/articles/10.3389/fphar.2023.1214756/full

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