Adenosine Methylation Level of miR-125a-5p Promotes Anti-PD-1 Therapy Escape through the Regulation of IGSF11/VSIG3 Expression

Adenosine Methylation Level of miR-125a-5p Promotes Anti-PD-1 Therapy Escape through the Regulation of IGSF11/VSIG3 Expression

Background: Despite encouraging anti-tumour activity in lung cancer, anti-PD-1 therapy has encountered increasing resistance to treatment. Several companion diagnostic assays have been performed to identify patients who may benefit from this immunotherapy and to adapt this therapy in case of acquire...

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Bibliographic Details
Main Authors: Gwenola Bougras-Cartron, Arulraj Nadaradjane, Marie-Pierre Joalland, Lisenn Lalier-Bretaudeau, Judith Raimbourg, Pierre-François Cartron
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Cancers
Subjects:
epitranscriptomics
methylation
adenosine
PD-1 therapy
lung cancer
Online Access:https://www.mdpi.com/2072-6694/15/12/3188

Internet

https://www.mdpi.com/2072-6694/15/12/3188

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