Searching for the real function of mTOR signaling in the regulation of PD-L1 expression
The mammalian target of rapamycin (mTOR), via forming two important complexes: mTOR complex 1 (mTORC1) and complex 2 (mTORC2), plays an important role in the regulation of immunity in addition to exerting many other biological funcions. Beyond its regulatory effects on immune cells, the mTOR axis al...
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Format: | Article |
Language: | English |
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Elsevier
2020-12-01
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Series: | Translational Oncology |
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Online Access: | http://www.sciencedirect.com/science/article/pii/S1936523320303399 |