Searching for the real function of mTOR signaling in the regulation of PD-L1 expression

The mammalian target of rapamycin (mTOR), via forming two important complexes: mTOR complex 1 (mTORC1) and complex 2 (mTORC2), plays an important role in the regulation of immunity in addition to exerting many other biological funcions. Beyond its regulatory effects on immune cells, the mTOR axis al...

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Bibliographic Details
Main Author: Shi-Yong Sun
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Translational Oncology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523320303399