Vinca herbacea Extract Suppresses NF-kB Signaling and Modulates SIRT1/AMPK/PGC1α Axis to Exert Antidiabetic Effects in Streptozotocin- Induced Diabetic Rats

Vinca herbacea Extract Suppresses NF-kB Signaling and Modulates SIRT1/AMPK/PGC1α Axis to Exert Antidiabetic Effects in Streptozotocin- Induced Diabetic Rats

Background and Objectives: AMPK/SIRT1/PGC1α signaling pathway has an important role in diabetic condition. Some natural products exert anti-diabetic effects by modulating this pathway and also by inhibition of NF-κB. Vinca herbacea has potent antioxidant and anti-inflammatory activities In the prese...

Full description

Bibliographic Details
Main Authors: Nasim Abedimanesh, Morteza Nouri, Kosar Mohammadnejad, Maedeh Barati, Elham Dabardani, Elahe Kakavand, Mohammad Reza Eskandari, Seyed Hojjat Hosseini, Seyede Momeneh Mohammadi, Iraj Jafari Anarkooli, Maryam Noubarani, Sina Andalib, Alireza Yazdinezhad, Behrooz Motlagh*
Format: Article
Language:English
Published: Iranian Society of Pharmacognosy 2022-01-01
Series:Research Journal of Pharmacognosy
Subjects:
nf-κb
pgc1α
sirt1
total antioxidant capacity
vinca herbacea
Online Access:http://www.rjpharmacognosy.ir/article_139926_627069d70e14559f63a1860060785d47.pdf

Internet

http://www.rjpharmacognosy.ir/article_139926_627069d70e14559f63a1860060785d47.pdf

Similar Items