Gene editing technology to improve antitumor T-cell functions in adoptive immunotherapy

Abstract Adoptive immunotherapy, in which tumor-reactive T cells are prepared in vitro for adoptive transfer to the patient, can induce an objective clinical response in specific types of cancer. In particular, chimeric antigen receptor (CAR)-redirected T-cell therapy has shown robust responses in h...

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Xehetasun bibliografikoak
Egile Nagusiak: Yusuke Ito, Satoshi Inoue, Yuki Kagoya
Formatua: Artikulua
Hizkuntza:English
Argitaratua: BMC 2024-03-01
Saila:Inflammation and Regeneration
Gaiak:
Sarrera elektronikoa:https://doi.org/10.1186/s41232-024-00324-7