Gene editing technology to improve antitumor T-cell functions in adoptive immunotherapy

Abstract Adoptive immunotherapy, in which tumor-reactive T cells are prepared in vitro for adoptive transfer to the patient, can induce an objective clinical response in specific types of cancer. In particular, chimeric antigen receptor (CAR)-redirected T-cell therapy has shown robust responses in h...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Yusuke Ito, Satoshi Inoue, Yuki Kagoya
Fformat: Erthygl
Iaith:English
Cyhoeddwyd: BMC 2024-03-01
Cyfres:Inflammation and Regeneration
Pynciau:
Mynediad Ar-lein:https://doi.org/10.1186/s41232-024-00324-7