The location and development of Replicon Cluster Domains in early replicating DNA [version 2; peer review: 2 approved, 1 approved with reservations]

Background: It has been known for many years that in metazoan cells, replication origins are organised into clusters where origins within each cluster fire near-synchronously. Despite clusters being a fundamental organising principle of metazoan DNA replication, the genomic location of origin cluste...

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Bibliographic Details
Main Authors: Marek Gierlinski, José A. da Costa-Nunes, Emma J. Haagensen, Takayo Sasaki, J. Julian Blow, David M. Gilbert
Format: Article
Language:English
Published: Wellcome 2023-08-01
Series:Wellcome Open Research
Subjects:
Online Access:https://wellcomeopenresearch.org/articles/8-158/v2