Nicotinamide Supplementation during the In Vitro Maturation of Oocytes Improves the Developmental Competence of Preimplantation Embryos: Potential Link to SIRT1/AKT Signaling

Nicotinamide Supplementation during the In Vitro Maturation of Oocytes Improves the Developmental Competence of Preimplantation Embryos: Potential Link to SIRT1/AKT Signaling

Nicotinamide (NAM), the amide form of vitamin B3, plays pivotal roles in regulating various cellular processes including energy production and maintenance of genomic stability. The current study aimed at deciphering the effect of NAM, when administered during in vitro maturation (IVM), on the develo...

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Bibliographic Details
Main Authors: Marwa El Sheikh, Ahmed Atef Mesalam, Muhammad Idrees, Tabinda Sidrat, Ayman Mesalam, Kyeong-Lim Lee, Il-Keun Kong
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Cells
Subjects:
Nicotinamide
AKT
SIRT1
hatching
maturation
ICM
Online Access:https://www.mdpi.com/2073-4409/9/6/1550

Internet

https://www.mdpi.com/2073-4409/9/6/1550

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