Stepwise in vitro screening of MMV pathogen box compounds against Plasmodium falciparum to identify potent antimalarial candidates

Development of resistance to deployed antimalarial drugs is inevitable and needs prompt and continuous discovery of novel candidate drugs. Therefore, the antimalarial activity of 125 compounds from the Medicine for Malaria Ventures (MMV) pathogen box was determined. Combining standard IC50 and norma...

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Bibliographic Details
Main Authors: Haddijatou Mbye, Fatoumata Bojang, Fatou Kene Jaiteh, Aminata Jawara, Bekai Njie, Simon Correa, Umberto D'Alessandro, Alfred Amambua-Ngwa
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:International Journal for Parasitology: Drugs and Drug Resistance
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211320723000209