Upregulation of outer membrane porin gene ompC contributed to enhancement of azithromycin susceptibility in multidrug-resistant Escherichia coli

Upregulation of outer membrane porin gene ompC contributed to enhancement of azithromycin susceptibility in multidrug-resistant Escherichia coli

ABSTRACTThe outer membrane (OM) in gram-negative bacteria contains proteins that regulate the passive or active uptake of small molecules for growth and cell function, as well as mediate the emergence of antibiotic resistance. This study aims to explore the potential mechanisms for restoring bacteri...

Full description

Bibliographic Details
Main Authors: Xing-Wei Luo, Peng-Liang Li, Ya-Jun Zhai, Yu-Shan Pan, Gong-Zheng Hu, Dan-Dan He
Format: Article
Language:English
Published: American Society for Microbiology 2024-04-01
Series:Microbiology Spectrum
Subjects:
azithromycin
membrane
ompC
mph(A)
conformation
Online Access:https://journals.asm.org/doi/10.1128/spectrum.03918-23

Internet

https://journals.asm.org/doi/10.1128/spectrum.03918-23

Similar Items