Cartilage degeneration is associated with activation of the PI3K/AKT signaling pathway in a growing rat experimental model of developmental trochlear dysplasia

Cartilage degeneration is associated with activation of the PI3K/AKT signaling pathway in a growing rat experimental model of developmental trochlear dysplasia

Introduction: Trochlear dysplasia is a commonly encountered lower extremity deformity in humans. However, the molecular mechanism of cartilage degeneration in trochlear dysplasia is unclear thus far. Objectives: The PI3K/AKT signaling pathway is known to be important for regulating the pathophysiolo...

Full description

Bibliographic Details
Main Authors: Wei Lin, Huijun Kang, Yingzhen Niu, Jinghui Niu, Chongyi Fan, Xunkai Feng, Fei Wang
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Journal of Advanced Research
Subjects:
Trochlear dysplasia
Patellar instability
PI3K/AKT
Cartilage degeneration
Osteoarthritis
Online Access:http://www.sciencedirect.com/science/article/pii/S2090123221000709

Internet

http://www.sciencedirect.com/science/article/pii/S2090123221000709

Similar Items