Lipid droplets dependent or independent cytoprotective activities of unsaturated fatty acids, Lorenzo’s oil and sulfo-N-succinimidyl oleate on 7-ketocholesterol-induced oxidative stress, organelle dysfunction and cell death on 158N and ARPE-19 cells: Cell targets and benefits of sulfo-N-succinimidyl oleate

Lipid droplets dependent or independent cytoprotective activities of unsaturated fatty acids, Lorenzo’s oil and sulfo-N-succinimidyl oleate on 7-ketocholesterol-induced oxidative stress, organelle dysfunction and cell death on 158N and ARPE-19 cells: Cell targets and benefits of sulfo-N-succinimidyl oleate

7-ketocholesterol is a cytotoxic oxysterol which is frequently increased in many chronic inflammatory and age-related diseases. Thus, the inhibition of the toxicity of 7-ketocholesterol is a major challenge to treat these diseases. 158N oligodendrocytes were used to evaluate the cytoprotective effec...

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Autori principali: Thomas Nury, Imen Ghzaiel, Aziz Hichami, Claudio Caccia, Valerio Leoni, Vivien Pires, Atanas G Atanasov, Amira Zarrouk, Gérard Lizard, Anne Vejux
Natura: Articolo
Lingua:English
Pubblicazione: Elsevier 2024-01-01
Serie:Current Research in Biotechnology
Soggetti:
7-ketocholesterol
α-linolenic acid
Eicosapentaenoic acid
Docosahexaenoic acid
Oleic acid
Erucic acid
Accesso online:http://www.sciencedirect.com/science/article/pii/S2590262824000212

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http://www.sciencedirect.com/science/article/pii/S2590262824000212

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