A randomized controlled trial of nebulized surfactant for the treatment of severe COVID-19 in adults (COVSurf trial)

A randomized controlled trial of nebulized surfactant for the treatment of severe COVID-19 in adults (COVSurf trial)

Abstract SARS-CoV-2 directly targets alveolar epithelial cells and can lead to surfactant deficiency. Early reports suggested surfactant replacement may be effective in improving outcomes. The aim of the study to assess the feasibility and efficacy of nebulized surfactant in mechanically ventilated...

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Bibliographic Details
Main Authors: Ahilanandan Dushianthan, Howard W. Clark, David Brealey, Danny Pratt, James B. Fink, Jens Madsen, Helen Moyses, Lewis Matthews, Tracy Hussell, Ratko Djukanovic, Martin Feelisch, Anthony D. Postle, Michael P. W. Grocott
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-47672-x

Internet

https://doi.org/10.1038/s41598-023-47672-x

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