Algorithm of molecular genetic investigation to identify hereditary <i>BRCA</i>-associated breast cancer

Background: About 30%  of cases of hereditary breast cancer (BC) are associated with the BRCA1 and BRCA2 gene mutations. The absence of the programs of mandatory genetic screening for hereditary BRCA-associated BC in Russia, as well as of an algorithm for molecular genetic testing does not allow ful...

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Main Authors: G. P. Snigireva, V. A. Rumyantseva, E. I. Novikova, N. N. Novitskaya, E. N. Telysheva, E. D. Khazins, E. G. Shaikhaev
Format: Article
Language:Russian
Published: MONIKI 2019-02-01
Series:Alʹmanah Kliničeskoj Mediciny
Subjects:
Online Access:https://www.almclinmed.ru/jour/article/view/966