Single molecule imaging of protein aggregation in Dementia: Methods, insights and prospects

The aggregation of misfolded proteins is a fundamental pathology in neurodegeneration which remains poorly understood due to its exceptional complexity and lack of appropriate characterization tools that can probe the role of the low concentrations of heterogeneous protein aggregates formed during t...

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Bibliographic Details
Main Authors: John S.H. Danial, David Klenerman
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996121000760