Paracrine interactions between mesenchymal stem cells affect substrate driven differentiation toward tendon and bone phenotypes.

We investigated substrate dependent paracrine signaling between subpopulations of bone marrow stromal cells (BMSCs) that may affect the formation, or perhaps malformation, of the regenerating tendon to bone enthesis. Polyacrylamide substrates approximating the elastic modulus of tendon granulation t...

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Bibliographic Details
Main Authors: Ram I Sharma, Jess G Snedeker
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3280320?pdf=render