Adoptive transfer of allergen-expressing B cells prevents IgE-mediated allergy

Adoptive transfer of allergen-expressing B cells prevents IgE-mediated allergy

IntroductionProphylactic strategies to prevent the development of allergies by establishing tolerance remain an unmet medical need. We previously reported that the transfer of autologous hematopoietic stem cells (HSC) expressing the major timothy grass pollen allergen, Phl p 5, on their cell surface...

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Bibliographic Details
Main Authors: Lisa Prickler, Ulrike Baranyi, Konstantinos Mengrelis, Anna Marianne Weijler, Verena Kainz, Bernhard Kratzer, Romy Steiner, Jasmin Mucha, Elisa Rudoph, Nina Pilat, Barbara Bohle, Herbert Strobl, Winfried Franz Pickl, Rudolf Valenta, Birgit Linhart, Thomas Wekerle
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Immunology
Subjects:
allergy
prophylaxis
tolerance
cell therapy
chimerism
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1286638/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1286638/full

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