In vivo targeted-imaging of mitochondrial acidification in an aristolochic acid I-induced nephrotoxicity mouse model by a fluorescent/photoacoustic bimodal probe

In vivo targeted-imaging of mitochondrial acidification in an aristolochic acid I-induced nephrotoxicity mouse model by a fluorescent/photoacoustic bimodal probe

Aristolochic acid I (AAI), a natural compound in aristolochia type Chinese medicinal herb, is generally acknowledged to have nephrotoxicity, which may be associated with mitophagy. Mitophagy is a cellular process with important functions that drive AAI-induced renal injury. Mitochondrial pH is curre...

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Bibliographic Details
Main Authors: Li Xu, Li Chen, Hongwen Liu, Xingwang Chen, Shenghang Zhang
Format: Article
Language:English
Published: Elsevier 2024-10-01
Series:Materials Today Bio
Subjects:
Aristolochic acid
Nephrotoxicity
In vivo mitophagy
Fluorescent imaging
Photoacoustic imaging
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006424003016

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http://www.sciencedirect.com/science/article/pii/S2590006424003016

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