CD137 Signaling Promotes Cardio-cerebral Angiogenesis in Mice Through Regulating Endothelial-mesenchymal Transition

CD137 Signaling Promotes Cardio-cerebral Angiogenesis in Mice Through Regulating Endothelial-mesenchymal Transition

ObjectiveTo explore whether CD137-CD137L signaling can promote cardio-cerebral angiogenesis in atherosclerotic plaques via endothelium-mesenchymal transition (End-MT).MethodsMouse brain-derived endothelial cells (Bend.3) and aortas from male mice were divided into the following groups: control (10 n...

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Bibliographic Details
Main Authors: WENG Jiayi, MA Xuexing, LI Yuan, SUN Kangyun
Format: Article
Language:zho
Published: Editorial Office of Laboratory Animal and Comparative Medicine 2021-10-01
Series:Shiyan dongwu yu bijiao yixue
Subjects:
atherosclerosis
angiogenesis
endothelium-mesenchymal transition
cd137
wnt
mice
Online Access:https://www.slarc.org.cn/dwyx/CN/10.12300/j.issn.1674-5817.2020.210

Internet

https://www.slarc.org.cn/dwyx/CN/10.12300/j.issn.1674-5817.2020.210

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