Endothelin-1 single nucleotide polymorphisms and risk of pulmonary metastatic osteosarcoma.

Pulmonary metastases are the major cause of death of osteosarcoma (OS) patients. Endothelin-1 (ET-1) reportedly plays an important role in OS metastasis. In the present study, we for the first time explored the association of ET-1 SNPs with the risk of pulmonary metastatic OS. We genotyped three SNP...

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Bibliographic Details
Main Authors: Xiaofang Zang, Yong Zhou, Zufa Huang, Chaoyue Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3771903?pdf=render