Ac-SDKP attenuates ER stress-stimulated collagen production in cardiac fibroblasts by inhibiting CHOP-mediated NF-κB expression

Ac-SDKP attenuates ER stress-stimulated collagen production in cardiac fibroblasts by inhibiting CHOP-mediated NF-κB expression

Inflammation and cardiac fibrosis are prevalent pathophysiologic conditions associated with hypertension, cardiac remodeling, and heart failure. Endoplasmic reticulum (ER) stress triggers the cells to activate unfolded protein responses (UPRs) and upregulate the ER stress chaperon, enzymes, and down...

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Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Hamid Suhail, Hongmei Peng, Khalid Matrougui, Nour-Eddine Rhaleb
Formáid: Alt
Teanga:English
Foilsithe / Cruthaithe: Frontiers Media S.A. 2024-03-01
Sraith:Frontiers in Pharmacology
Ábhair:
Ac-SDKP
ER stress
UPRs
inflammation
collagen
human cardiac fibroblast
Rochtain ar líne:https://www.frontiersin.org/articles/10.3389/fphar.2024.1352222/full

Ar líne

https://www.frontiersin.org/articles/10.3389/fphar.2024.1352222/full

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