The effect of pH on thrombin generation–An unrecognized potential source of variation

Abstract Background When CO2 escapes from plasma, the pH of the plasma increases. In samples left open or kept in long‐term storage, the pH may increase considerably. Assays in which the ratio of plasma sample relative to the total volume including reagents is high may be sensitive to the pH of the...

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Bibliographic Details
Main Authors: Søren Risom Kristensen, Jette Nybo, Shona Pedersen
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:Research and Practice in Thrombosis and Haemostasis
Subjects:
Online Access:https://doi.org/10.1002/rth2.12289