Apoptosis-mediated ADAM10 activation removes a mucin barrier promoting T cell efferocytosis
Abstract Efferocytic clearance of apoptotic cells in general, and T cells in particular, is required for tissue and immune homeostasis. Transmembrane mucins are extended glycoproteins highly expressed in the cell glycocalyx that function as a barrier to phagocytosis. Whether and how mucins may be re...
| Auteurs principaux: | , , , , , , , , , , , , |
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| Format: | Article |
| Langue: | English |
| Publié: |
Nature Portfolio
2024-01-01
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| Collection: | Nature Communications |
| Accès en ligne: | https://doi.org/10.1038/s41467-023-44619-8 |