The Role of Macroautophagy and Chaperone-Mediated Autophagy in the Pathogenesis and Management of Hepatocellular Carcinoma

The Role of Macroautophagy and Chaperone-Mediated Autophagy in the Pathogenesis and Management of Hepatocellular Carcinoma

Hepatocarcinogenesis is a long process with a complex pathophysiology. The current therapeutic options for HCC management, during the advanced stage, provide short-term survival ranging from 10–14 months. Autophagy acts as a double-edged sword during this process. Recently, two main autophagic pathw...

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Bibliographic Details
Main Authors: Anastasia D. Karampa, Anna C. Goussia, Georgios K. Glantzounis, Eleftheria M. Mastoridou, Nikolaos-Andreas T. Anastasopoulos, Antonia V. Charchanti
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Cancers
Subjects:
hepatocellular carcinoma
macroautophagy
chaperone-mediated autophagy
chemoresistance
Online Access:https://www.mdpi.com/2072-6694/14/3/760

Internet

https://www.mdpi.com/2072-6694/14/3/760

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