Imbalanced pattern completion vs. separation in cognitive disease: network simulations of synaptic pathologies predict a personalized therapeutics strategy
<p>Abstract</p> <p>Background</p> <p>Diverse Mouse genetic models of neurodevelopmental, neuropsychiatric, and neurodegenerative causes of impaired cognition exhibit at least four convergent points of synaptic malfunction: 1) Strength of long-term potentiation (LTP), 2)...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2010-08-01
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Series: | BMC Neuroscience |
Online Access: | http://www.biomedcentral.com/1471-2202/11/96 |