Gamma-aminobutyric acid and glutamate/glutamine levels in the dentate nucleus and periaqueductal gray with episodic and chronic migraine: a proton magnetic resonance spectroscopy study

Abstract Background The pathogenesis of migraine chronification remains unclear. Functional and structural magnetic resonance imaging studies have shown impaired functional and structural alterations in the brains of patients with chronic migraine. The cerebellum and periaqueductal gray (PAG) play p...

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Bibliographic Details
Main Authors: Wei Wang, Xueyan Zhang, Xiaoyan Bai, Yingkui Zhang, Ziyu Yuan, Hefei Tang, Zhiye Li, Zhangxuan Hu, Yaqing Zhang, Xueying Yu, Binbin Sui, Yonggang Wang
Format: Article
Language:English
Published: BMC 2022-07-01
Series:The Journal of Headache and Pain
Subjects:
Online Access:https://doi.org/10.1186/s10194-022-01452-6