Colonic biopsies to assess the neuropathology of Parkinson's disease and its relationship with symptoms.

The presence of Lewy bodies and Lewy neurites (LN) has been demonstrated in the enteric nervous system (ENS) of Parkinson's disease (PD) patients. The aims of the present research were to use routine colonoscopy biopsies (1) to analyze, in depth, enteric pathology throughout the colonic submuco...

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Main Authors: Thibaud Lebouvier, Michel Neunlist, Stanislas Bruley des Varannes, Emmanuel Coron, Anne Drouard, Jean-Michel N'Guyen, Tanguy Chaumette, Maddalena Tasselli, Sébastien Paillusson, Mathurin Flamand, Jean-Paul Galmiche, Philippe Damier, Pascal Derkinderen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2939055?pdf=render