CD56bright cells respond to stimulation until very advanced age revealing increased expression of cellular protective proteins SIRT1, HSP70 and SOD2

Abstract Background NK cells are cytotoxic lymphocytes of innate immunity composed of: cytotoxic CD56dim and immunoregulatory CD56bright cells. The study aimed to analyze the expression of cellular protective proteins: sirtuin 1 (SIRT1), heat shock protein 70 (HSP70) and manganese superoxide dismuta...

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Bibliographic Details
Main Authors: Lucyna Kaszubowska, Jerzy Foerster, Daria Schetz, Zbigniew Kmieć
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Immunity & Ageing
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12979-018-0136-5