Ligand-induced endocytosis and nuclear localization of angiotensin II receptors expressed in CHO cells

A construct (AT1R-NF) containing a "Flag" sequence added to the N-terminus of the rat AT1 receptor was stably expressed in Chinese hamster ovary cells and quantified in the cell membrane by confocal microscopy after reaction with a fluorescein-labeled anti-Flag monoclonal antibody. Angiote...

Full description

Bibliographic Details
Main Authors: A.J. Merjan, C.A. Kanashiro, J.E. Krieger, S.W. Han, A.C.M. Paiva
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2001-09-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000900011