Histone Modification Marks Strongly Regulate CDH1 Promoter In Prostospheres As A Model Of Prostate Cancer Stem Like Cells

Objective Cadherin-1 (CDH1) plays an important role in the metastasis, while expression of this protein is under control of epigenetic changes on its gene promoter. Therefore we evaluated both DNA methylation (DNAmet) and histone modification marks of CDH1 in prostate cancer stem like cells (PCSLCs...

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Bibliographic Details
Main Authors: Fatemeh Shokraii, Maryam Moharrami, Nasrin Motamed, Maryam Shahhoseini, Mehdi Totonchi, Vahid Ezzatizadeh, Javad Firouzi, Pardis Khosravani, Marzieh Ebrahimi
Format: Article
Language:English
Published: Royan Institute (ACECR), Tehran 2019-02-01
Series:Cell Journal
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Online Access:https://celljournal.org/journal/article/abstract/5702