Maternal exposure to prostaglandin E2 modifies expression of Wnt genes in mouse brain – An autism connection

Maternal exposure to prostaglandin E2 modifies expression of Wnt genes in mouse brain – An autism connection

Prostaglandin E2 (PGE2) is a lipid signaling molecule important for brain development and function. Various genetic and environmental factors can influence the level of PGE2 and increase the risk of developing Autism Spectrum Disorder (ASD). We have previously shown that in neuronal cell lines and m...

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Bibliographic Details
Main Authors: Ravneet Rai-Bhogal, Christine Wong, Ashby Kissoondoyal, Jennilee Davidson, Hongyan Li, Dorota A. Crawford
Format: Article
Language:English
Published: Elsevier 2018-07-01
Series:Biochemistry and Biophysics Reports
Subjects:
Lipids
Prostaglandin E2
Gene expression
Wnt signaling pathway
β-catenin
Autism Spectrum Disorder
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580816303193

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http://www.sciencedirect.com/science/article/pii/S2405580816303193

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