Drug metabolism-related gene ABCA1 augments temozolomide chemoresistance and immune infiltration abundance of M2 macrophages in glioma

Drug metabolism-related gene ABCA1 augments temozolomide chemoresistance and immune infiltration abundance of M2 macrophages in glioma

Abstract Gliomas are the most prevalent primary tumor in the central nervous system, with an abysmal 5-year survival rate and alarming mortality. The current standard management of glioma is maximum resection of tumors followed by postoperative chemotherapy with temozolomide (TMZ) or radiotherapy. L...

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Bibliographic Details
Main Authors: Yuanliang Yan, Yuanhong Liu, Qiuju Liang, Zhijie Xu
Format: Article
Language:English
Published: BMC 2023-09-01
Series:European Journal of Medical Research
Subjects:
Glioma
ABCA1
Temozolomide
Chemosensitivity
Drug efflux transporter
Online Access:https://doi.org/10.1186/s40001-023-01370-6

Internet

https://doi.org/10.1186/s40001-023-01370-6

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