High-content fluorescence bioassay investigates pore formation, ion channel modulation and cell membrane lysis induced by venoms

High-content fluorescence bioassay investigates pore formation, ion channel modulation and cell membrane lysis induced by venoms

Venoms comprise highly sophisticated bioactive molecules modulating ion channels, receptors, coagulation factors, and the cellular membranes. This array of targets and bioactivities requires advanced high-content bioassays to facilitate the development of novel envenomation treatments and biotechnol...

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Bibliographic Details
Main Authors: Simon Kramer, Charan Kotapati, Yuanzhao Cao, Bryan G. Fry, Nathan J. Palpant, Glenn F. King, Fernanda C. Cardoso
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Toxicon: X
Subjects:
High-throughput
High-content
Bioassay
ion channel
Pore-forming
Membrane lysis
Online Access:http://www.sciencedirect.com/science/article/pii/S2590171024000018

Internet

http://www.sciencedirect.com/science/article/pii/S2590171024000018

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