Notch Signaling and Cross-Talk in Hypoxia: A Candidate Pathway for High-Altitude Adaptation
Hypoxia triggers complex inter- and intracellular signals that regulate tissue oxygen (O<sub>2</sub>) homeostasis, adjusting convective O<sub>2</sub> delivery and utilization (i.e., metabolism). Human populations have been exposed to high-altitude hypoxia for thousands of yea...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-03-01
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Series: | Life |
Subjects: | |
Online Access: | https://www.mdpi.com/2075-1729/12/3/437 |