DLEC1 Expression Is Modulated by Epigenetic Modifications in Hepatocelluar Carcinoma Cells: Role of HBx Genotypes

Deleted in Lung and Esophageal Cancer 1 (DLEC1) is a functional tumor suppressor gene (TSG). It has been found to be silenced in a variety of human cancers including hepatocellular carcinoma (HCC). The silencing of DLEC1 can be modulated by epigenetic modifications, such as DNA hypermethylation and...

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Bibliographic Details
Main Authors: Wei Ning Chen, Huixing Feng, Dandan Niu
Format: Article
Language:English
Published: MDPI AG 2010-09-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/2/3/1689/